Efficacy of Probiotics in Rheumatoid Arthritis and Spondyloarthritis: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
Sanchez · 2022 · Nutrients
What this paper found
Meta-analysis across 13 RCTs. CRP reduced significantly (mean difference −3.04 mg/L, p<0.001) but DAS28 disease activity score showed no consistent change after excluding high-risk-of-bias trials. Biochemical signal without clinical translation; strain-dependent, L. casei and L. acidophilus show the strongest individual signals.
Why this is on the map
Foundational evidence, predates the 2024–2026 platform window but remains the best available meta-analysis on probiotics in spondyloarthritis. Read with that age caveat.
On the map under this thread
DOI: 10.3390/nu14020354· opens in a new tab. The full paper is on the publisher’s site, not here.
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