Comprehensive Phenotyping of Circulating T- and B-Cell Subsets in Patients with Ankylosing Spondylitis Associated with Crohn's Disease.
Rubinstein A · 2026 · Cells
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What this paper found
Comparing blood immune cells from people with ankylosing spondylitis plus Crohn's disease against those with either condition alone, the combined group had more regulatory T cells and a distinct pattern of memory T and B cells. It is a small pilot, but it suggests AS with gut disease is immunologically its own thing, not simply AS and Crohn's added together.
Why this is on the map
First cell-level profile of the AS-plus-Crohn's overlap; 13 patients, so a lead rather than a conclusion.
On the map under this thread
DOI: 10.3390/cells15171580 · opens in a new tab. The full paper is on the publisher’s site, not here.
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