Male sexual dysfunction associated with TNF-α inhibitors: an indication-stratified global pharmacovigilance analysis.
Chu Y · 2026 · Frontiers in pharmacology
Reading the original? How to read a paper.
What this paper found
Searching the WHO global side-effect database, researchers found no overall link between TNF blockers and male sexual dysfunction, but among reports from people with ankylosing spondylitis there was a modest excess for adalimumab and etanercept that did not hold up at the level of specific symptoms. The authors call it hypothesis-generating, which is fair: worth knowing about, not a reason to change treatment.
Why this is on the map
Raises a question patients rarely get to ask; the evidence is weak and the paper says so.
On the map under these threads
DOI: 10.3389/fphar.2026.1915246 · opens in a new tab. The full paper is on the publisher’s site, not here.
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