Clinical Outcomes of Venous Thromboembolism in Patients with Ankylosing Spondylitis vs. Other Immune-mediated Inflammatory Diseases: Insights from the RIETE Registry.
Chopard R · 2026 · Thrombosis and haemostasis
Reading the original? How to read a paper.
What this paper found
In a registry of over 112,000 people treated for blood clots, those with ankylosing spondylitis had similar death and bleeding rates to people with other inflammatory diseases, but were seven times more likely than non-inflammatory patients to have a second clot, and those who stopped blood thinners before a year did worse. If you have AS and have had a clot, longer anticoagulation may be warranted; it is worth raising with whoever manages it.
Why this is on the map
Clot recurrence is a new outcome for the map; this is the largest dataset on AS and venous thromboembolism.
On the map under this thread
DOI: 10.1055/a-2722-7327 · opens in a new tab. The full paper is on the publisher’s site, not here.
Related papers on the board
Papers sharing one or more threads with this one.
Long-term functional and radiological outcomes among survivors of ankylosing spondylitis-associated cervical spine fractures: a cross-sectional follow-up study.
North American Spine Society journal
Among 97 survivors of neck fractures linked to ankylosing spondylitis, followed for a median of four years, most lived independently with mild neck pain and low disability, 96 percent of fractures had healed solidly, and half of those with spinal cord injury recovered fully. These fractures are dangerous at the time, but for those who come through them the long-term picture is better than most people would expect.
Plasma Proteomics Identifies Molecular Signatures and Biomarkers Associated with High Structural Damage in Ankylosing Spondylitis
Arthritis & Rheumatology
Measuring hundreds of blood proteins in people with ankylosing spondylitis, researchers found a five-protein signature, driven by platelet and tissue-remodelling proteins rather than classic inflammation markers, that identified those with heavy structural damage with high accuracy in a separate validation group. Bone damage in AS seems to run partly on a different track from inflammation, and a blood test for it looks feasible.
Preconception, pregnancy and postpartum periods in spondyloarthritis: Unmet needs and challenges from a patients and rheumatologists surveys
Joint Bone Spine
Surveys of French women with spondyloarthritis and their rheumatologists found that pregnancy is not discouraged and usually goes well, but women rated their worry about flares highly, had gaps in knowledge about biologics in pregnancy and delivery, and only a quarter of rheumatologists knew the pregnancy guidelines. The information gap is on both sides of the consultation.
Risk of peripheral artery disease following ankylosing spondylitis, 2012–2023: a nationwide cohort study in South Korea
Scandinavian Journal of Rheumatology
Following 2,846 people with ankylosing spondylitis and ten times as many matched controls in South Korea for four years, AS was linked to a 40 percent higher rate of peripheral artery disease, with the largest excess in women under 60. Circulation in the legs is another thing to keep an eye on, especially for younger women with AS.