Paradoxical psoriasis in axial spondyloarthritis and rheumatoid arthritis treated with b/tsDMARDs: a retrospective cohort study.
Harman H · 2026 · Clinical rheumatology
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What this paper found
Among 1,588 people on biologics for axial spondyloarthritis or rheumatoid arthritis, about 2 percent developed a psoriasis-like rash caused by the drug, almost always a TNF blocker, with smoking the only independent risk factor; stopping the drug cleared it in most, and switching to a non-TNF drug worked. If a new rash appears on a TNF blocker, it may be the drug, and there are good alternatives.
Why this is on the map
Puts a number and a risk factor on a side effect patients ask about; the TNF thread's safety papers mostly cover infection.
On the map under these threads
DOI: 10.1007/s10067-026-08417-z · opens in a new tab. The full paper is on the publisher’s site, not here.
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