Risk of Cancer According to Duration of Targeted Therapy Exposure in Spondyloarthritis: A Nationwide Cohort Study From the French Health Insurance Database
Tankovic Karine · 2026 · Arthritis & Rheumatology
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What this paper found
Following 56,591 people with spondyloarthritis in France for a median of five years, those taking a targeted therapy for more than six months a year had slightly lower overall cancer risk than those taking it less. Staying on a TNF, IL-17 or JAK drug did not raise cancer risk in this very large real-world group, which addresses a common worry about long-term treatment.
Why this is on the map
Largest cancer-safety dataset across all three drug classes on the map; reassuring where older TNF-only studies were mixed.
On the map under these threads
DOI: 10.1002/art.70297 · opens in a new tab. The full paper is on the publisher’s site, not here.
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